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  Enzyme & Pathway

The information shown in this page was generated using the cross-referenced linkage within public domain database between their strains and BCRC related strains. Usually the information provided from public domain databases varies with diffent confidences and errors, BCRC provides the related information here at best effort, but BCRC doesn't take the responsibility about the correctness of the information provided here.

D-alanine--D-lactate ligase
Name :Vancomycin/teicoplanin A-type resistance protein VanA (EC 6.1.2.1) (D-alanine--D-lactate ligase) (VanA ligase)
Reaction :D-alanine + (R)-lactate + ATP <--> D-alanyl-D-lactate + ADP + phosphate
UNIPROT ID : P25051      BioCyc ID: MONOMER-15466
D-lactate dehydrogenase
Name :D-lactate dehydrogenase VanH-A (Dehydrogenase) (Dehydrogenase VanH) (Pyruvate dehydrogenase) (VanH) (VanH protein) (VanH protein, D-specific alpha-keto acid dehydrogenase) (EC 1.1.1.-) (Vancomycin resistance protein VanH / D-lactate dehydrogenase) (EC 1.1.1.28)
Reaction :(R)-lactate + NAD+ <--> pyruvate + NADH + H+
UNIPROT ID : Q7B609      BioCyc ID: MONOMER-15467
D-alanyl-D-alanine dipeptidase
Name :D-alanyl-D-alanine dipeptidase (D-Ala-D-Ala dipeptidase) (EC 3.4.13.22) (Vancomycin B-type resistance protein VanX)
Reaction :D-alanyl-D-alanine + H2O <--> 2 D-alanine
UNIPROT ID : Q06241      BioCyc ID: MONOMER-15475
D-alanine--D-lactate ligase
Name :D-alanine--D-alanine ligase (EC 6.3.2.4) (D-Ala-D-Ala ligase) (D-alanylalanine synthetase)
Reaction :D-alanine + (R)-lactate + ATP <--> D-alanyl-D-lactate + ADP + phosphate
UNIPROT ID : Q9XCR4      BioCyc ID: MONOMER-15478
peptidoglycan D,D transpeptidase
Name :Penicillin-binding protein PBP5
Reaction :2 a peptidoglycan dimer (E. faeciums) + H+ <--> a peptidoglycan tetramer with a D,D cross-link (Enterococcus faecium) + D-alanine
UNIPROT ID : Q93T65      BioCyc ID: MONOMER-15537

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