| tetracenomycin third ring cyclase |
| Name : | Tetracenomycin polyketide synthesis protein TcmJ |
| Reaction : | 3,5-dioxo-6-[4,5,7-trihydroxy-3-(3-oxobutanoyl)naphthalen-2-yl]hexanoate <--> tetracenomycin F2 + H2O |
|
UNIPROT ID :
P16558
BioCyc ID:
MONOMER-18609
|
|
| tetracenomycin C polyketide synthase |
| Name : | Tetracenomycin C polyketide putative beta-ketoacyl synthase 1 (EC 2.3.1.-) |
| Reaction : | 10 malonyl-CoA + H2O + 9 H+ <--> 3,5,7,9,11,13,15,17,19-nonaoxoicosanoate + 10 CO2 + 10 coenzyme A |
|
UNIPROT ID :
P16538
BioCyc ID:
MONOMER-18610
|
|
| tetracenomycin C polyketide synthase |
| Name : | Tetracenomycin C polyketide putative beta-ketoacyl synthase 2 (EC 2.3.1.-) |
| Reaction : | 10 malonyl-CoA + H2O + 9 H+ <--> 3,5,7,9,11,13,15,17,19-nonaoxoicosanoate + 10 CO2 + 10 coenzyme A |
|
UNIPROT ID :
P16539
BioCyc ID:
MONOMER-18611
|
|
| tetracenomycin C polyketide synthase |
| Name : | Tetracenomycin C polyketide synthase acyl carrier protein (ACP) |
| Reaction : | 10 malonyl-CoA + H2O + 9 H+ <--> 3,5,7,9,11,13,15,17,19-nonaoxoicosanoate + 10 CO2 + 10 coenzyme A |
|
UNIPROT ID :
P12884
BioCyc ID:
MONOMER-18612
|
|
| tetracenomycin F1 monooxygenase |
| Name : | Tetracenomycin-F1 monooxygenase (EC 1.13.12.21) (Tetracenomycin polyketide synthesis hydroxylase TcmH) |
| Reaction : | tetracenomycin F1 + oxygen <--> tetracenomycin D3 + H2O + H+ |
|
UNIPROT ID :
P39889
BioCyc ID:
MONOMER-18103
|
|
| tetracenomycin aromatase |
| Name : | Multifunctional cyclase-dehydratase-3-O-methyl transferase TcmN (EC 2.1.1.-) |
| Reaction : | 3,5,7,9,11,13,15,17,19-nonaoxoicosanoate <--> 3,5-dioxo-6-[4,5,7-trihydroxy-3-(3-oxobutanoyl)naphthalen-2-yl]hexanoate + 2 H2O |
|
UNIPROT ID :
P16559
BioCyc ID:
MONOMER-18604
|
|
| tetracenomycin B3 8-O-methyl transferase |
| Name : | Tetracenomycin polyketide synthesis 8-O-methyl transferase TcmO (EC 2.1.1.-) |
| Reaction : | S-adenosyl-L-methionine + tetracenomycin B3 <--> tetracenomycin E + S-adenosyl-L-homocysteine + H+ |
|
UNIPROT ID :
P39896
BioCyc ID:
MONOMER-18605
|
|
| tetracenomycin E C-9 O-methyltransferase |
| Name : | Tetracenomycin polyketide synthesis O-methyltransferase TcmP (EC 2.1.1.-) |
| Reaction : | S-adenosyl-L-methionine + tetracenomycin E <--> tetracenomycin A2 + S-adenosyl-L-homocysteine |
|
UNIPROT ID :
P39887
BioCyc ID:
MONOMER-18606
|
|
| tetracenomycin A2 C4,C4A,C12A hydroxylase |
| Name : | Tetracenomycin polyketide synthesis hydroxylase TcmG (EC 1.14.13.-) |
| Reaction : | tetracenomycin A2 + 2 NADPH + 2 oxygen + 2 H+ <--> tetracenomycin C + 2 NADP+ + H2O |
|
UNIPROT ID :
P39888
BioCyc ID:
MONOMER-18607
|
|
| tetracenomycin F2 cyclase |
| Name : | Tetracenomycin F2 cyclase (EC 4.2.1.154) (Tetracenomycin polyketide synthesis protein TcmI) |
| Reaction : | tetracenomycin F2 <--> tetracenomycin F1 + H2O |
|
UNIPROT ID :
P39890
BioCyc ID:
MONOMER-18608
|
|
