| 8-demethyl-8-α-L-rhamnosyl tetracenomycin-C 2'-O-methyltransferase |
| Name : | 8-demethyl-8-alpha-L-rhamnosyl tetracenomycin-C 2'-O-methyltransferase (EC 2.1.1.305) (O-methyltransferase I) |
| Reaction : | S-adenosyl-L-methionine + 8-demethyl-8-alpha-L-rhamnosyl-tetracenomycin C <--> 8-demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C + S-adenosyl-L-homocysteine + H+ |
|
UNIPROT ID :
Q9AJU2
BioCyc ID:
MONOMER-18589
|
|
| 8-demethyl-8-(2-methoxy-α-L-rhamnosyl)-tetracenomycin-C 3'-O-methyltransferase |
| Name : | 8-demethyl-8-(2-methoxy-alpha-L-rhamnosyl)-tetracenomycin-C 3'-O-methyltransferase (EC 2.1.1.306) (O-methyltransferase II) |
| Reaction : | S-adenosyl-L-methionine + 8-demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C <--> 8-demethyl-8-(2,3-O-dimethyl-alpha-L-rhamnosyl)-tetracenomycin C + S-adenosyl-L-homocysteine + H+ |
|
UNIPROT ID :
Q9AJU1
BioCyc ID:
MONOMER-18590
|
|
| 8-demethyl-8-(2,3-dimethoxy-α-L-rhamnosyl)-tetracenomycin-C 4'-O-methyltransferase |
| Name : | 8-demethyl-8-(2,3-dimethoxy-alpha-L-rhamnosyl)-tetracenomycin-C 4'-O-methyltransferase (EC 2.1.1.307) (O-methyltransferase III) |
| Reaction : | S-adenosyl-L-methionine + 8-demethyl-8-(2,3-O-dimethyl-alpha-L-rhamnosyl)-tetracenomycin C <--> 12-demethyl-elloramycin + S-adenosyl-L-homocysteine + H+ |
|
UNIPROT ID :
Q9AJU0
BioCyc ID:
MONOMER-18591
|
|
| 8-demethyltetracenomycin C rhamnosyltransferase |
| Name : | Elloramycin glycosyltransferase ElmGT (EC 2.4.1.331) |
| Reaction : | 8-demethyltetracenomycin C + dTDP-beta-L-rhamnose <--> 8-demethyl-8-alpha-L-rhamnosyl-tetracenomycin C + dTDP + H+ |
|
UNIPROT ID :
Q9F2F9
BioCyc ID:
MONOMER-18592
|
|
| elloramycin polyketide synthase |
| Name : | Ketoacyl synthase alpha |
| Reaction : | 10 malonyl-CoA + H2O + 9 H+ <--> 3,5,7,9,11,13,15,17,19-nonaoxoicosanoate + 10 CO2 + 10 coenzyme A |
|
UNIPROT ID :
A8KQX2
BioCyc ID:
MONOMER-18593
|
|
| elloramycin polyketide synthase |
| Name : | Ketoacyl synthase beta |
| Reaction : | 10 malonyl-CoA + H2O + 9 H+ <--> 3,5,7,9,11,13,15,17,19-nonaoxoicosanoate + 10 CO2 + 10 coenzyme A |
|
UNIPROT ID :
A8KQX7
BioCyc ID:
MONOMER-18594
|
|
| elloramycin polyketide synthase |
| Name : | Acyl carrier protein |
| Reaction : | 10 malonyl-CoA + H2O + 9 H+ <--> 3,5,7,9,11,13,15,17,19-nonaoxoicosanoate + 10 CO2 + 10 coenzyme A |
|
UNIPROT ID :
A8KQY0
BioCyc ID:
MONOMER-18595
|
|
| elloramycin aromatase |
| Name : | Aromatase |
| Reaction : | 3,5,7,9,11,13,15,17,19-nonaoxoicosanoate <--> 3,5-dioxo-6-[4,5,7-trihydroxy-3-(3-oxobutanoyl)naphthalen-2-yl]hexanoate + 2 H2O |
|
UNIPROT ID :
A8KQY4
BioCyc ID:
MONOMER-18596
|
|
| elloramycin third ring cyclase |
| Name : | ElmJ (Third ring cyclase) |
| Reaction : | 3,5-dioxo-6-[4,5,7-trihydroxy-3-(3-oxobutanoyl)naphthalen-2-yl]hexanoate <--> tetracenomycin F2 + H2O |
|
UNIPROT ID :
Q9L4X8
BioCyc ID:
MONOMER-18597
|
|
| tetracenomycin F2 cyclase |
| Name : | Tcm F2 cyclase |
| Reaction : | tetracenomycin F2 <--> tetracenomycin F1 + H2O |
|
UNIPROT ID :
Q9L4X9
BioCyc ID:
MONOMER-18598
|
|
| tetracenomycin F1 monooxygenase |
| Name : | Tcm F1 monooxygenase (TcmF1 monooxygenase) |
| Reaction : | tetracenomycin F1 + oxygen <--> tetracenomycin D3 + H2O + H+ |
|
UNIPROT ID :
Q9L4Y0
BioCyc ID:
MONOMER-18599
|
|
| tetracenomycin D3 3-O-methyltransferase |
| Name : | C3 O-methyltransferase |
| Reaction : | S-adenosyl-L-methionine + tetracenomycin D3 <--> tetracenomycin B3 + S-adenosyl-L-homocysteine |
|
UNIPROT ID :
A8KQY8
BioCyc ID:
MONOMER-18600
|
|
| tetracenomycin B3 9-O-methyltransferase |
| Name : | Carboxyl O-methyltransferase |
| Reaction : | S-adenosyl-L-methionine + tetracenomycin B3 <--> tetracenomycin B2 + S-adenosyl-L-homocysteine |
|
UNIPROT ID :
A8KQZ3
BioCyc ID:
MONOMER-18601
|
|
| tetracenomycin B2 oxygenase |
| Name : | Tcm B2 oxygenase (TcmB2 oxygenase) |
| Reaction : | tetracenomycin B2 + 2 NADPH + 2 oxygen + 2 H+ <--> 8-demethyltetracenomycin C + 2 NADP+ + H2O |
|
UNIPROT ID :
Q9L4Y1
BioCyc ID:
MONOMER-18602
|
|
| 12-demethyl-elloramycin C12a O-methyltransferase |
| Name : | S-adenosyl-L-methionine-dependent methyltransferase (EC 2.1.1.-) |
| Reaction : | S-adenosyl-L-methionine + 12-demethyl-elloramycin <--> elloramycin + S-adenosyl-L-homocysteine + H+ |
|
UNIPROT ID :
A8KQU1
BioCyc ID:
MONOMER-18603
|
|
