| UWM6 dehydratase |
| Name : | JadF |
| Reaction : | UWM6 <--> prejadomycin + H2O |
|
UNIPROT ID :
Q5U915
BioCyc ID:
MONOMER-16085
|
|
| prejadomycin monooxygenase/dehydratase |
| Name : | JadH |
| Reaction : | prejadomycin + NAD(P)H + oxygen + H+ <--> 8-methyltetraphene-1,5,6,11,12-pentol + NAD(P)+ + 2 H2O |
|
UNIPROT ID :
Q5U913
BioCyc ID:
MONOMER-16086
|
|
| dehydrorabelomycin dioxygenase |
| Name : | JadG |
| Reaction : | dehydrorabelomycin + oxygen <--> 3-(2-formyl-6-hydroxy-4-methylphenyl)-8-hydroxy-1,4-dioxonaphthalene-2-carboxylate + H+ |
|
UNIPROT ID :
Q5U914
BioCyc ID:
MONOMER-16087
|
|
| dTDP-4-amino-4,6-dideoxy-D-glucose transaminase |
| Name : | 4-dehydrase |
| Reaction : | 2-oxoglutarate + dTDP-viosamine <--> L-glutamate + dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose |
|
UNIPROT ID :
Q9ZGH0
BioCyc ID:
MONOMER-16950
|
|
| dTDP-4-amino-4,6-dideoxy-D-glucose deaminase |
| Name : | dTDP-4-amino-4,6-dideoxy-D-glucose ammonia-lyase (EC 4.3.1.30) (dTDP-D-quinovose dehydrogenase) (dTDP-D-quinovose:S-adenosyl-L-methionine 1-oxidoreductase) (EC 1.1.99.-) |
| Reaction : | S-adenosyl-L-methionine + dTDP-viosamine + a reduced unknown electron carrier <--> dTDP-3-dehydro-4,6-deoxy-alpha-D-glucose + ammonium + L-methionine + 5'-deoxyadenosine + an oxidized unknown electron carrier + H+ |
|
UNIPROT ID :
Q9ZGH1
BioCyc ID:
MONOMER-16951
|
|
| dTDP-glucose 4,6-dehydratase |
| Name : | dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) |
| Reaction : | dTDP-alpha-D-glucose <--> dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose + H2O |
|
UNIPROT ID :
Q9ZGH3
BioCyc ID:
MONOMER-16952
|
|
| dTDP-3-oxo-3,4,6-trideoxy-α-D-glucopyranose transaminase |
| Name : | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose transaminase (EC 2.6.1.106) |
| Reaction : | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose + 2-oxoglutarate <--> dTDP-3-dehydro-4,6-deoxy-alpha-D-glucose + L-glutamate |
|
UNIPROT ID :
Q9ZGH4
BioCyc ID:
MONOMER-16953
|
|
| dTDP-3-amino-3,4,6-trideoxy-α-D-glucopyranose N,N-dimethyltransferase |
| Name : | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose (EC 2.1.1.234) |
| Reaction : | 2 S-adenosyl-L-methionine + dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose <--> 2 S-adenosyl-L-homocysteine + dTDP-D-desosamine + 2 H+ |
|
UNIPROT ID :
Q9ZGH6
BioCyc ID:
MONOMER-16954
|
|
| glucose-1-phosphate thymidylyltransferase |
| Name : | Glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) |
| Reaction : | dTTP + alpha-D-glucopyranose 1-phosphate + H+ <--> dTDP-alpha-D-glucose + diphosphate |
|
UNIPROT ID :
Q9ZGH2
BioCyc ID:
MONOMER-16971
|
|
| narbomycin C14-monooxygenase |
| Name : | Cytochrome P450 monooxygenase PikC (EC 1.14.15.33) (Cytochrome P450 monooxygenase PicK) (Narbomycin C-12 hydroxylase) (Pikromycin synthase CYP107L1) |
| Reaction : | narbomycin + 2 a reduced ferredoxin [iron-sulfur] cluster + oxygen + 2 H+ <--> neopikromycin + 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O |
|
UNIPROT ID :
O87605
BioCyc ID:
MONOMER-18405
|
|
| narbonolide desosaminyltransferase |
| Name : | 10-deoxymethynolide desosaminyltransferase (EC 2.4.1.277) |
| Reaction : | dTDP-D-desosamine + narbonolide <--> narbomycin + dTDP + H+ |
|
UNIPROT ID :
Q9ZGH7
BioCyc ID:
MONOMER-18406
|
|
| editing thioesterase |
| Name : | Thioesterase PikA5 (EC 3.1.2.-) (Editing thioesterase) (Thioesterase II) (TEII) (Type II thioesterase) |
| Reaction : | malonyl-CoA + 5 (S)-methylmalonyl-CoA + 5 NADPH + 11 H+ <--> 10-deoxymethynolide + 6 CO2 + 6 coenzyme A + 5 NADP+ + 2 H2O |
|
UNIPROT ID :
Q9ZGI1
BioCyc ID:
MONOMER-18410
|
|
| 10-deoxymethynolide synthase |
| Name : | Narbonolide/10-deoxymethynolide synthase PikA1, modules 1 and 2 (EC 2.3.1.239) (EC 2.3.1.240) (Narbonolide/10-deoxymethynolide synthase PikAI) (Pikromycin polyketide synthase component PikAI) (Pikromycin PKS component PikAI) (Type I modular polyketide synthase PikAI) (PKS) |
| Reaction : | malonyl-CoA + 5 (S)-methylmalonyl-CoA + 5 NADPH + 11 H+ <--> 10-deoxymethynolide + 6 CO2 + 6 coenzyme A + 5 NADP+ + 2 H2O |
|
UNIPROT ID :
Q9ZGI5
BioCyc ID:
MONOMER-18411
|
|
| 10-deoxymethynolide synthase |
| Name : | Narbonolide/10-deoxymethynolide synthase PikA2, modules 3 and 4 (EC 2.3.1.239) (EC 2.3.1.240) (Narbonolide/10-deoxymethynolide synthase PikAII) (Pikromycin polyketide synthase component PikAII) (Pikromycin PKS component PikAII) (Type I modular polyketide synthase PikAII) (PKS) |
| Reaction : | malonyl-CoA + 5 (S)-methylmalonyl-CoA + 5 NADPH + 11 H+ <--> 10-deoxymethynolide + 6 CO2 + 6 coenzyme A + 5 NADP+ + 2 H2O |
|
UNIPROT ID :
Q9ZGI4
BioCyc ID:
MONOMER-18412
|
|
| 10-deoxymethynolide synthase |
| Name : | Narbonolide/10-deoxymethynolide synthase PikA3, module 5 (EC 2.3.1.239) (EC 2.3.1.240) (Narbonolide/10-deoxymethynolide synthase PikAIII) (Pikromycin polyketide synthase component PikAIII) (Pikromycin PKS component PikAIII) (Type I modular polyketide synthase PikAIII) (PKS) |
| Reaction : | malonyl-CoA + 5 (S)-methylmalonyl-CoA + 5 NADPH + 11 H+ <--> 10-deoxymethynolide + 6 CO2 + 6 coenzyme A + 5 NADP+ + 2 H2O |
|
UNIPROT ID :
Q9ZGI3
BioCyc ID:
MONOMER-18413
|
|
| 10-deoxymethynolide synthase |
| Name : | Narbonolide/10-deoxymethynolide synthase PikA4, module 6 (EC 2.3.1.239) (EC 2.3.1.240) (Narbonolide/10-deoxymethynolide synthase PikAIV) (Pikromycin polyketide synthase component PikAIV) (Pikromycin PKS component PikAIV) (Type I modular polyketide synthase PikAIV) (PKS) |
| Reaction : | malonyl-CoA + 5 (S)-methylmalonyl-CoA + 5 NADPH + 11 H+ <--> 10-deoxymethynolide + 6 CO2 + 6 coenzyme A + 5 NADP+ + 2 H2O |
|
UNIPROT ID :
Q9ZGI2
BioCyc ID:
MONOMER-18414
|
|
