| 3-hydroxy-D-kynurenine methyltransferase |
| Name : | Methyltransferase |
| Reaction : | S-adenosyl-L-methionine + 3-hydroxy-D-kynurenine <--> S-adenosyl-L-homocysteine + 3-hydroxy-4-methyl-D-kynurenine + H+ |
|
UNIPROT ID :
D6R245
BioCyc ID:
MONOMER-19501
|
|
| 3-hydroxy-D-kynurenine methyltransferase |
| Name : | Methyltransferase |
| Reaction : | S-adenosyl-L-methionine + 3-hydroxy-D-kynurenine <--> S-adenosyl-L-homocysteine + 3-hydroxy-4-methyl-D-kynurenine + H+ |
|
UNIPROT ID :
D6R232
BioCyc ID:
MONOMER-19502
|
|
| 3-hydroxy-4-methyl-D-kynurenine hydrolase |
| Name : | Kynureninase (EC 3.7.1.3) (L-kynurenine hydrolase) |
| Reaction : | 3-hydroxy-4-methyl-D-kynurenine + H2O <--> 3-hydroxy-4-methylanthranilate + L-alanine + H+ |
|
UNIPROT ID :
D6R244
BioCyc ID:
MONOMER-19503
|
|
| 3-hydroxy-4-methyl-D-kynurenine hydrolase |
| Name : | Kynureninase |
| Reaction : | 3-hydroxy-4-methyl-D-kynurenine + H2O <--> 3-hydroxy-4-methylanthranilate + L-alanine + H+ |
|
UNIPROT ID :
D6R233
BioCyc ID:
MONOMER-19504
|
|
| kynurenine formamidase |
| Name : | Aryl formamidase |
| Reaction : | N-Formyl-L-kynurenine + H2O <--> L-kynurenine + formate + H+ |
|
UNIPROT ID :
D6R242
BioCyc ID:
MONOMER-19505
|
|
| tryptophan 2,3-dioxygenase |
| Name : | Tryptophan 2,3-dioxygenase (TDO) (EC 1.13.11.11) (Tryptamin 2,3-dioxygenase) (Tryptophan oxygenase) (TO) (TRPO) (Tryptophan pyrrolase) (Tryptophanase) |
| Reaction : | L-tryptophan + oxygen <--> N-Formyl-L-kynurenine |
|
UNIPROT ID :
D6R243
BioCyc ID:
MONOMER-19506
|
|
| 3-hydroxy-4-methyl-anthranilate carrier protein |
| Name : | 4-MHA carrier protein |
| Reaction : | 3-hydroxy-4-methylanthranilyl-adenylate + a holo-[AcmD acyl-carrier protein] <--> a 3-hydroxy-4-methyl-anthranilyl-[AcmD acyl-carrier protein] + AMP + H+ |
|
UNIPROT ID :
D6R237
BioCyc ID:
MONOMER-19507
|
|
| 3-hydroxy-4-methyl-anthranilate pentapeptide lactone synthase |
| Name : | Peptide synthetase |
| Reaction : | 2 S-adenosyl-L-methionine + a 3-hydroxy-4-methyl-anthranilyl-L-threonyl-D-valyl-[AcmD acyl-carrier protein] + L-valine + L-proline + glycine + 3 ATP <--> 3-hydroxy-4-methyl-anthranilate pentapeptide lactone + 2 S-adenosyl-L-homocysteine + a holo-[AcmD acyl-carrier protein] + 3 ADP + 3 phosphate + 5 H+ |
|
UNIPROT ID :
D6R240
BioCyc ID:
MONOMER-19508
|
|
| 3-hydroxy-4-methyl-anthranilate pentapeptide lactone synthase |
| Name : | Peptide synthetase |
| Reaction : | a 3-hydroxy-4-methyl-anthranilyl-[AcmD acyl-carrier protein] + L-threonine + L-valine + 2 ATP <--> a 3-hydroxy-4-methyl-anthranilyl-L-threonyl-D-valyl-[AcmD acyl-carrier protein] + 2 ADP + 2 phosphate + 2 H+ |
|
UNIPROT ID :
D6R239
BioCyc ID:
MONOMER-19509
|
|
| 3-hydroxy-4-methylanthranilate adenylyltransferase |
| Name : | Peptide synthetase |
| Reaction : | 3-hydroxy-4-methylanthranilate + ATP + H+ <--> 3-hydroxy-4-methylanthranilyl-adenylate + diphosphate |
|
UNIPROT ID :
D6R238
BioCyc ID:
MONOMER-19510
|
|
