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The information shown in this page was generated using the cross-referenced linkage within public domain database between their strains and BCRC related strains. Usually the information provided from public domain databases varies with diffent confidences and errors, BCRC provides the related information here at best effort, but BCRC doesn't take the responsibility about the correctness of the information provided here.

tetracenomycin third ring cyclase
Name :Tetracenomycin polyketide synthesis protein TcmJ
Reaction :3,5-dioxo-6-[4,5,7-trihydroxy-3-(3-oxobutanoyl)naphthalen-2-yl]hexanoate <--> tetracenomycin F2 + H2O
UNIPROT ID : P16558      BioCyc ID: MONOMER-18609
tetracenomycin C polyketide synthase
Name :Tetracenomycin C polyketide putative beta-ketoacyl synthase 1 (EC 2.3.1.-)
Reaction :10 malonyl-CoA + H2O + 9 H+ <--> 3,5,7,9,11,13,15,17,19-nonaoxoicosanoate + 10 CO2 + 10 coenzyme A
UNIPROT ID : P16538      BioCyc ID: MONOMER-18610
tetracenomycin C polyketide synthase
Name :Tetracenomycin C polyketide putative beta-ketoacyl synthase 2 (EC 2.3.1.-)
Reaction :10 malonyl-CoA + H2O + 9 H+ <--> 3,5,7,9,11,13,15,17,19-nonaoxoicosanoate + 10 CO2 + 10 coenzyme A
UNIPROT ID : P16539      BioCyc ID: MONOMER-18611
tetracenomycin C polyketide synthase
Name :Tetracenomycin C polyketide synthase acyl carrier protein (ACP)
Reaction :10 malonyl-CoA + H2O + 9 H+ <--> 3,5,7,9,11,13,15,17,19-nonaoxoicosanoate + 10 CO2 + 10 coenzyme A
UNIPROT ID : P12884      BioCyc ID: MONOMER-18612
tetracenomycin F1 monooxygenase
Name :Tetracenomycin-F1 monooxygenase (EC 1.13.12.21) (Tetracenomycin polyketide synthesis hydroxylase TcmH)
Reaction :tetracenomycin F1 + oxygen <--> tetracenomycin D3 + H2O + H+
UNIPROT ID : P39889      BioCyc ID: MONOMER-18103
tetracenomycin aromatase
Name :Multifunctional cyclase-dehydratase-3-O-methyl transferase TcmN (EC 2.1.1.-)
Reaction :3,5,7,9,11,13,15,17,19-nonaoxoicosanoate <--> 3,5-dioxo-6-[4,5,7-trihydroxy-3-(3-oxobutanoyl)naphthalen-2-yl]hexanoate + 2 H2O
UNIPROT ID : P16559      BioCyc ID: MONOMER-18604
tetracenomycin B3 8-O-methyl transferase
Name :Tetracenomycin polyketide synthesis 8-O-methyl transferase TcmO (EC 2.1.1.-)
Reaction :S-adenosyl-L-methionine + tetracenomycin B3 <--> tetracenomycin E + S-adenosyl-L-homocysteine + H+
UNIPROT ID : P39896      BioCyc ID: MONOMER-18605
tetracenomycin E C-9 O-methyltransferase
Name :Tetracenomycin polyketide synthesis O-methyltransferase TcmP (EC 2.1.1.-)
Reaction :S-adenosyl-L-methionine + tetracenomycin E <--> tetracenomycin A2 + S-adenosyl-L-homocysteine
UNIPROT ID : P39887      BioCyc ID: MONOMER-18606
tetracenomycin A2 C4,C4A,C12A hydroxylase
Name :Tetracenomycin polyketide synthesis hydroxylase TcmG (EC 1.14.13.-)
Reaction :tetracenomycin A2 + 2 NADPH + 2 oxygen + 2 H+ <--> tetracenomycin C + 2 NADP+ + H2O
UNIPROT ID : P39888      BioCyc ID: MONOMER-18607
tetracenomycin F2 cyclase
Name :Tetracenomycin F2 cyclase (EC 4.2.1.154) (Tetracenomycin polyketide synthesis protein TcmI)
Reaction :tetracenomycin F2 <--> tetracenomycin F1 + H2O
UNIPROT ID : P39890      BioCyc ID: MONOMER-18608

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