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The information shown in this page was generated using the cross-referenced linkage within public domain database between their strains and BCRC related strains. Usually the information provided from public domain databases varies with diffent confidences and errors, BCRC provides the related information here at best effort, but BCRC doesn't take the responsibility about the correctness of the information provided here.

pyruvate carboxylase
Name :Pyruvate carboxylase (EC 6.4.1.1) (Pyruvic carboxylase) (PCB)
Reaction :pyruvate + hydrogencarbonate + ATP <--> oxaloacetate + ADP + phosphate + H+
UNIPROT ID : O93918      BioCyc ID: MONOMER-13631
cis-aconitate decarboxylase
Name :Cis-aconitate decarboxylase (CAD) (EC 4.1.1.6) (Aconitate decarboxylase) (Cis-aconitic acid decarboxylase)
Reaction :cis-aconitate + H+ <--> CO2 + itaconate
UNIPROT ID : B3IUN8      BioCyc ID: MONOMER-13632
aconitase
Name :Aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.-)
Reaction :citrate <--> cis-aconitate + H2O
UNIPROT ID : O74699      BioCyc ID: MONOMER-13634
lovastatin nonaketide synthase
Name :Lovastatin nonaketide synthase, enoyl reductase component (EC 2.3.1.161)
Reaction :S-adenosyl-L-methionine + 9 malonyl-CoA + lovastatin nonaketide synthase + 11 NADPH + 19 H+ <--> dihydromonacolin L-[lovastatin nonaketide synthase] + S-adenosyl-L-homocysteine + 9 CO2 + 9 coenzyme A + 11 NADP+ + 6 H2O
UNIPROT ID : Q9Y7D0      BioCyc ID: MONOMER-18781
lovastatin nonaketide synthase
Name :Lovastatin nonaketide synthase, polyketide synthase component (LNKS) (EC 2.3.1.161)
Reaction :S-adenosyl-L-methionine + 9 malonyl-CoA + lovastatin nonaketide synthase + 11 NADPH + 19 H+ <--> dihydromonacolin L-[lovastatin nonaketide synthase] + S-adenosyl-L-homocysteine + 9 CO2 + 9 coenzyme A + 11 NADP+ + 6 H2O
UNIPROT ID : Q9Y8A5      BioCyc ID: MONOMER-18782
monacolin L hydroxylase
Name :Dihydromonacolin L monooxygenase LovA (EC 1.14.14.124) (EC 1.14.14.125) (Dihydromonacolin L hydroxylase) (Monacolin L hydroxylase)
Reaction :monacolin L acid + a reduced [NADPH-hemoprotein reductase] + oxygen <--> monacolin J acid + an oxidized [NADPH-hemoprotein reductase] + H2O
UNIPROT ID : Q9Y7C8      BioCyc ID: MONOMER-18784
monacolin J acid methylbutanoate transferase
Name :Monacolin J acid methylbutanoyltransferase (EC 2.3.1.238) (Lovastatin hydrolase) (Simvastatin synthase LovD) (SV synthase)
Reaction :monacolin J acid + (S)-2-methylbutanoyl-[2-methylbutanoate polyketide synthase] <--> lovastatin acid + a holo-2-methylbutanoyl-[polyketide synthase]
UNIPROT ID : Q9Y7D1      BioCyc ID: MONOMER-18785
2-methylbutanoate polyketide synthase
Name :Lovastatin diketide synthase LovF (LDKS) (EC 2.3.1.244)
Reaction :S-adenosyl-L-methionine + 2 malonyl-CoA + a holo-2-methylbutanoyl-[polyketide synthase] + 2 NADPH + 3 H+ <--> (S)-2-methylbutanoyl-[2-methylbutanoate polyketide synthase] + S-adenosyl-L-homocysteine + 2 CO2 + 2 coenzyme A + 2 NADP+ + H2O
UNIPROT ID : Q9Y7D5      BioCyc ID: MONOMER-18789

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