|Taxonomy Citation ID||Reference|
|9203||Rogosa, M., and Hansen, P.A. "Nomenclatural considerations of certain species of Lactobacillus Beijerinck. Request for an opinion." Int. J. Syst. Bacteriol. (1971) 21:177-186. [No PubMed record available.]|
|9202||Orla-Jensen, S.: The lactic acid bacteria. Host & Son, Copenhagen (1919). pp. 1-118. [No PubMed record available.]|
|3809||Weiss, N., Schillinger, U., and Kandler, O. "Lactobacillus lactis, Lactobacillus leichmannii and Lactobacillus bulgaricus subjective synonyms of Lactobacillus delbrueckii subsp. lactis comb. nov. and Lactobacillus delbrueckii subsp. bulgaricus comb. nov." Syst. Appl. Microbiol. (1983) 4:552-557. [No PubMed record available.]|
|3808||Skerman, V.B.D., McGowan, V., and Sneath, P.H.A. (editors): "Approved lists of bacterial names." Int. J. Syst. Bacteriol. (1980) 30:225-420. [See 'Approved Lists of Bacterial Names' LinkOut below.]|
|2754||VALIDATION LIST No. 14. Int. J. Syst. Bacteriol. (1984) 34:270-271.||17717||
van de Guchte M,
( 2006 )
The complete genome sequence of Lactobacillus bulgaricus reveals extensive and ongoing reductive evolution.
PMID : 16754859 DOI : 10.1073/pnas.0603024103 PMC : PMC1482600 DOI : 10.1073/pnas.0603024103 PMC : PMC1482600
Lactobacillus delbrueckii ssp. bulgaricus (L. bulgaricus) is a representative of the group of lactic acid-producing bacteria, mainly known for its worldwide application in yogurt production. The genome sequence of this bacterium has been determined and shows the signs of ongoing specialization, with a substantial number of pseudogenes and incomplete metabolic pathways and relatively few regulatory functions. Several unique features of the L. bulgaricus genome support the hypothesis that the genome is in a phase of rapid evolution. (i) Exceptionally high numbers of rRNA and tRNA genes with regard to genome size may indicate that the L. bulgaricus genome has known a recent phase of important size reduction, in agreement with the observed high frequency of gene inactivation and elimination; (ii) a much higher GC content at codon position 3 than expected on the basis of the overall GC content suggests that the composition of the genome is evolving toward a higher GC content; and (iii) the presence of a 47.5-kbp inverted repeat in the replication termination region, an extremely rare feature in bacterial genomes, may be interpreted as a transient stage in genome evolution. The results indicate the adaptation of L. bulgaricus from a plant-associated habitat to the stable protein and lactose-rich milk environment through the loss of superfluous functions and protocooperation with Streptococcus thermophilus.